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Index > Protein center > Elovl1(Gene name) > Mouse
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  • Elovl1 (Gene name),
  • Elongation of very long chain fatty acids protein 1 (Protein name ),  ELOV1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Elovl1(Ssc1);
    Protein name:
    Elongation of very long chain fatty acids protein 1;
    Alternative:
    ELOVL fatty acid elongase 1(ELOVL FA elongase 1);3-keto acyl-CoA synthase Elovl1;Very-long-chain 3-oxoacyl-CoA synthase 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Involved in the biosynthesis of C26 fatty acids and sphingolipids. Condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids. Exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Important for sphingolipid biosynthesis.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    279
    Sequence:
    50:
    MEAVVNLYHE | LMKHADPRIQ | SYPLMGSPLL | ITSILLTYVY | FILSLGPRIM | 
    100:
    ANRKPFQLRG | FMIVYNFSLV | ILSLYIVYEF | LMSGWLSTYT | WRCDPIDFSN | 
    150:
    SPEALRMVRV | AWLFMLSKVI | ELMDTVIFIL | RKKDGQVTFL | HVFHHSVLPW | 
    200:
    SWWWGIKIAP | GGMGSFHAMI | NSSVHVVMYL | YYGLSALGPV | AQPYLWWKKH | 
    250:
    MTAIQLIQFV | LVSLHISQYY | FMPSCNYQYP | IIIHLIWMYG | TIFFILFSNF | 
    279:
    WYHSYTKGKR | LPRAVQQNGA | PATTKVKAN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Elongation of very long chain fatty acids protein 1
    Cat.:
    E13834h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Elongation of very long chain fatty acids protein 1
    Cat.:
    E13834m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Elongation of very long chain fatty acids protein 1
    Cat.:
    U13834m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Elongation of very long chain fatty acids protein 1
    Cat.:
    U13834h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse Elongation of very long chain fatty acids protein 1
    Polyclonal Antibody for Mouse Elongation of very long chain fatty acids protein 1
    Monoclonal Antibody for Mouse Elongation of very long chain fatty acids protein 1
    Monoclonal Antibody for Mouse Elongation of very long chain fatty acids protein 1
    Protein for Mouse Elongation of very long chain fatty acids protein 1
    Protein for Mouse Elongation of very long chain fatty acids protein 1

    R&D Technical Data

    s

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    s
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤3.9%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤7.7%

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
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    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    99

    91-103

    Plasma

    98

    93-106

     

     

     

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
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    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    92-105%

    90-101%

    95-105%

    92-109%

    Saliva(n=3)

    89-95%

    93105%

    89-94%

    90-106%

    heparin plasma(n=5)

    93-104%

     

    94-110%

    101-111%

    91-110%

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Role of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids."
      Tvrdik P. , Westerberg R. , Silve S. , Asadi A. , Jakobsson A. , Cannon B. , Loison G. , Jacobsson A.
      J. Cell Biol.149:707-718(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY
      strain: BALB/c.
      tissue: Liver.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Mammary tumor.
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 78-279
      strain: C57BL/6J.
      tissue: Embryo.
    4. 4.
      "Fatty acid transport protein 4 (FATP4) prevents light-induced degeneration of cone and rod photoreceptors by inhibiting RPE65 isomerase."
      Li S. , Lee J. , Zhou Y. , Gordon W.C. , Hill J.M. , Bazan N.G. , Miner J.H. , Jin M.
      J. Neurosci.33:3178-3189(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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